Dr. Sam Russell, having narrowly escaped being convicted of the murder of his first wife, knows he is in big trouble when he wakes up in his car one morning with blood under his nails, no memory of what happened the day before, and his second wife missing.
After the death of her estranged brother, defense attorney Kali O'Brien goes to Tucson, Arizona, to settle his estate, comfort her sister, and prove he was not responsible for the two murders he had been suspected of committing.