François Pignon, a very bland sort of man who works as an accountant in a condom factory, is about to be fired. His new neighbour comes up with an idea to prevent such a thing from happening: he creates photos and then spreads the rumor that François is gay so that the factory management might be afraid they'll be sued for sexual discrimination. Of course, nothing happens as it should, but the changes in François Pignon's life-- and other people's...

Two Frenchmen must go to South America to save the local shaman's soul from the evil forces.