A successful jazz musician whose marriage is on the rocks, a man in black who threatens to expose him, a young mechanic with links to a mobster, and the mobster's moll are all riders on the lost highway, trapped in their worlds of desire, destiny and unknown destination.

Stephen and Bloom are brothers who have been con artists since they were kids. Stephen is the mastermind, while Bloom is the main character of Stephen's stories. As adults, they travel the world and never enlist the same people twice in their cons, except for their consistent sidekick, the mysterious and primarily silent Bang Bang, a Japanese woman who just appeared in their lives one day and happens to have a penchant for blowing things up. As Bloom...