Elsa Mars is the proprietor of a troupe of human "curiosities" on a desperate journey of survival in the sleepy hamlet of Jupiter, Florida, in 1952. Her menagerie of performers includes a two-headed, telepathic twin, a take-charge bearded lady, a vulnerable strongman, and his three-breasted wife. But strange emergence of an entity will savagely threaten the lives of the townsfolk and freaks alike.