After being bitten by a radioactive spider on a school field trip, Peter Parker finds himself gaining spider-like qualities. Adopting the name Spider-Man, Peter first uses his new skills to make money, but when the Green Goblin, another altered super-human, kills Peter's uncle, he swears to use his "spider-skills" to fight evil. Along the way he has to juggle a new job as a local reporter, and a budding romance with a beautiful former-classmate, MJ....

Nerdy Peter Parker acquires super powers after a bite from a genetically modified spider. When his uncle is murdered he sets out to avenge his death, and he must battle the evil villain, the Green Goblin.