Dr. David Henry, forced to deliver his own twins during a snowstorm in 1964 with only a nurse to help him, makes a decision that has far-reaching effects on his life, and the lives of his wife and son, when his infant daughter is born with Down Syndrome, and in a vain attempt to protect his wife, he orders the nurse to take the baby to an institution.

When antiwar activists Arthur and Annie Pope blew up a napalm lab in 1971, they accidentally blinded a janitor working late. Since then, the Popes and their children have stayed together by staying a step ahead of the law, running from state to state, job to job, assumed identity to assumed identity. But now elder son Danny is 17. He's ready to stop running from a past he had nothing to do with, ready to start making his own future.

Years after an unspeakable tragedy tore their lives apart, two sets of parents (Reed Birney and Ann Dowd, Jason Isaacs and Martha Plimpton), agree to talk privately in an attempt to move forward. In Fran Kranz' writing and directing debut, he thoughtfully examines their journey of grief, anger and acceptance by coming face-to-face with the ones who have been left behind.