Willem Dafoe plays a mercenary sent by a shadowy corporation to the untamed wilderness of Tasmania to track down a tiger thought to be extinct, whose genetic code holds the secret to a dangerous weapon.

Willem Dafoe's Academy Award®-nominated performance as Vincent Van Gogh highlights this Julian Schnabel film that journeys inside the world and mind of the artist.

In this powerful, true story, boxer Salamo Arouch (Willem Dafoe) is interned in the Nazi death camp Auschwitz with his family and friends. For the amusement of his captors, Salamo is forced to fight his fellow inmates in brutal contests that send the loser to the gas showers. Salamo's prowess in the ring is both his salvation and his nightmare, as his "victories" condemn others to death. Still he fights on, hoping to somehow save his father and friends...perhaps...

During World War II, a mysterious stranger is rescued from a fiery plane crash. The American allies care for him and the dangerous secrets from his past come to light.

In the year 2019, an unknown plague has transformed the world's population into vampires but the blood supply is quickly running out. A clandestine group of vampires led by researcher Edward Dalton makes a remarkable discovery that has the power to save the human race from extinction.

Willem Dafoe in an erotic thriller centered on one couple's final hours as a looming, apocalyptic disaster grows near.

Internationally reknown oceanographer Steve Zissou and his crew - Team Zissou - set sail on an expedition to hunt down the mysterious, always elusive, possibly non-existant Jaguar Shark that supposedly killed Zissou's partner during the documentary filming of their latest adventure. On this journey, Steve's crew are joined by a young airline co-pilot, who may or may not be Zissou's son, a beautiful journalist who has been assigned to write a profile...

Abel Ferrara’s first dramatic feature since 2014’s Pasolini reteams the filmmaker and his frequent lead Willem Dafoe, who delivers a career-best performance as the title character, an older American expat living in Rome with his young wife and their daughter. Disoriented by his past misgivings and subsequent, unexpected blows to his self-esteem, Tommaso wades through this late chapter of his life with an increasingly impaired grasp on reality...

Fraternal twins Murphy (Norman Reedus, THE WALKING DEAD) and Connor (Sean Patrick Flanery, POWDER) become vigilantes after killing two members of the Russian Mafia in self-defense. After both experience an epiphany, the brothers set out to rid Boston of evil while being tracked down by FBI agent Paul Smecker (Willem Dafoe, SPIDERMAN, PLATOON, SHADOW OF THE VAMPIRE) in this stylish and violent crowd-pleaser.

Cult author and David Lynch collaborator Barry Gifford’s gritty autobiographical stories of growing up in the 1950s (narrated by Willem Dafoe, Lili Taylor and Matt Dillon) provide the backdrop for a jazzy, impressionistic portrait of a vanished Chicago.